The Saframycins are naturally occurring antibiotics with an interesting bisquinone structure. The first and only synthesis of saframycin B is described herein. The interesting aspects of this synthesis are the convergent approach and the method of stereochemical control. Studies directed towards adapting the saframycin B synthesis to the synthesis of saframycins A and S are also described. These studies have resulted in the synthesis
of a compound structurally related to the saframycins but so far unreported in the literature.
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| Identifer | oai:union.ndltd.org:RICE/oai:scholarship.rice.edu:1911/15930 |
| Date | January 1985 |
| Creators | SACHLEBEN, RICHARD ALAN |
| Source Sets | Rice University |
| Language | English |
| Detected Language | English |
| Type | Thesis, Text |
| Format | application/pdf |
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