Formation of the skeleton of renieramycin A was achieved through sequential condensations of piperazinedione and substituted benzaldehydes. One of the key reactions of this synthesis, oxidation of benzylic position, produced hydroxylated compound 62 (see p. 22 in dissertation for illustration). Further elaboration of 62 has resulted in N-methyl 65 (p. 22), an important precursor to renieramycin A.
| Identifer | oai:union.ndltd.org:RICE/oai:scholarship.rice.edu:1911/13323 |
| Date | January 1988 |
| Creators | Tun, Min Min |
| Contributors | Fukuyama, T. |
| Source Sets | Rice University |
| Language | English |
| Detected Language | English |
| Type | Thesis, Text |
| Format | 137 p., application/pdf |
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