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Využití vysoce účinné iontové chromatografie ve farmaceutické analýze organických aniontů a kationtů / Pharmaceutical application of high performance ion chromatography in analysis of organic anions and cations

The thesis is focused on application of ion chromatography in pharmaceutical analyses of organic ions. Ion chromatography is increasingly used in the field of pharmaceutical analysis. This includes the analysis of impurities and metabolites. In the first part of this thesis, ion chromatography is compared with common separation techniques used in pharmacy, such as gas chromatography and high performance liquid chromatography. In the second part development and validation of methods of ion chromatography for purity evaluation and quality control of active pharmaceutical substances Rivastigmine hemitartrate and Pramipexole hydrochloride were carried out. Key words: ion chromatography, reversed-phase chromatography, ion-pair chromatography, ion-exclusion chromatography, ion-exchange chromatography, GC, HPLC

Identiferoai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:285473
Date January 2010
CreatorsČujová, Sabína
ContributorsČabala, Radomír, Pacáková, Věra
Source SetsCzech ETDs
LanguageEnglish
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/masterThesis
Rightsinfo:eu-repo/semantics/restrictedAccess

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