Magister Chirurgiae Dentium (MChD) / Chlorhexidine has been established as the gold standard against which new
chemical plaque control agents are tested (Jones, 1997). The addition of alcohol
in a chlorhexidine mouthwash had been widely used, however the comparative
efficacy of alcohol free chlorhexidine mouthwash had not fully been explored in
this study, two chlorhexidine mouthwash preparations were tested to evaluate
their comparative efficacy in the treatment of periodontal disease. Aims: To
assess the efficacy of alcohol-free chlorhexidine mouth wash in comparison to
alcohol containing chlorhexidine mouth wash.
Objectives: To determine pre- and post- operative clinical parameters and
microbial load in the management of patients with chronic periodontitis.
Methodology: A double blinded randomised control trial was conducted.
Patients diagnosed with active chronic periodontitis were included in the study
and randomised to either a test (chlorhexidine without alcohol) or control group
(chlorhexidine with alcohol). A total of 50 patients were selected for the study.
Results: The Wilcoxon Signed Rank test was used to test the difference
between the pre-post pair per clinical indicator and Bana-Zyme. The differences
between before and after treatment per indicator were significant at P<0.001 for
respectively Paroex and Peridex. These values demonstrated the difference
between the clinical parameters taken before the treatment and six weeks post
treatment.
Conclusion: Both mouth wash solutions with and without alcohol had proven
to reduce the microbial load as shown by the BANA-Zyme test, with the alcohol
containing solution having been more effective.
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uwc/oai:etd.uwc.ac.za:11394/6573 |
| Date | January 2018 |
| Creators | Mpungose, Siphesihle P. |
| Contributors | Jeftha, Anthea |
| Publisher | University of the Western Cape |
| Source Sets | South African National ETD Portal |
| Language | English |
| Detected Language | English |
| Rights | University of the Western Cape |
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