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The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection

Includes abstract. / Includes bibliographical references (leaves 101-111). / Interleukin-4 receptor alpha (IL-4Ra) signaling, mediated by the ligands IL-4 and IL- 13, is important for effective host protection during murine Nippostrongylus brasiliensis (N. brasiliensis) and Schistosoma mansoni (S. manson!) infection. Among other cell types, IL-4Ra responsive smooth muscle cells influence immunological responses and are needed for host protection during N. brasiliensis and S. mansoni infection.

Identiferoai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uct/oai:localhost:11427/12245
Date January 2011
CreatorsBrombacher, Tiroyaone M H
ContributorsBrombacher, Frank
PublisherUniversity of Cape Town, Faculty of Health Sciences, Division of Immunology
Source SetsSouth African National ETD Portal
LanguageEnglish
Detected LanguageEnglish
TypeDoctoral Thesis, Doctoral, PhD
Formatapplication/pdf

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