Background: Uppsala University Hospital Sweden is planning to implement a closed loop medication system, with the aim of reducing risk prescriptions from the point of drugs being prescribed to orders being produced and administered. With inspiration from Leuven, an advanced system for pharmaceutical validation; System Assisted Pharmaceutical VALidation (SAPVAL) is planned to be developed. Aim: The aim of the study was to obtain a deeper understanding of clinical rules as an important element for building the SAPVAL system. This study will review and further develop a first set of clinical rules and validate these on the intended study population. Methods: A retrospective cross-sectional study was performed to validate the clinical rules on a study population of 500 patients who were discharged from Uppsala University Hospital between May to July 2020. The clinical rules were applied cross-sectionally based on patient data from the electronic health records. From the total generated alerts, 10 % was randomly selected for assessment of the clinical relevance. Results: The clinical rules generated 893 alerts in 500 patients, of which 84 % alerts still remained two days after the patient was admitted to the hospital or at discharge. From the randomly selected alerts, 26 % were deemed clinically relevant. Conclusions: The developed clinical rules generate a large number of alerts for risk prescriptions for inpatients at Uppsala University hospital. The majority of the alerts remained during the care period and approximately a quarter of them were considered to be clinically relevant to remedy.
Identifer | oai:union.ndltd.org:UPSALLA1/oai:DiVA.org:uu-449406 |
Date | January 2021 |
Creators | Johansson, Ebba |
Publisher | Uppsala universitet, Institutionen för farmaci |
Source Sets | DiVA Archive at Upsalla University |
Language | Swedish |
Detected Language | English |
Type | Student thesis, info:eu-repo/semantics/bachelorThesis, text |
Format | application/pdf |
Rights | info:eu-repo/semantics/openAccess |
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