The prospect of the work presented in this thesis has been to engineer Cre recombinase to recognize and recombine a sequence from an HIV-1 Long Terminal Repeat (LTR), characterize the recombination proficiency of the evolved recombinase in mammalian cells and explore the potential of the recombinase for a novel antiretroviral strategy.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:24909 |
| Date | 26 September 2006 |
| Creators | Sarkar, Indrani |
| Contributors | Buchholz, Frank, Stewart, Francis, Hauber, Joachim |
| Publisher | Technische Universität Dresden |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | doc-type:doctoralThesis, info:eu-repo/semantics/doctoralThesis, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
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