The scientific case made by the AUTHOR’S comparative Brassica oleracea genomics work is presented through 5 peer reviewed research papers. In order to achieve a comprehensive understanding of the evolution of B. oleracea the identification of unique genome characteristics, established using comparative genomics, is required. The genome characteristics established within these papers deliver significant contributions to original knowledge. These include a detailed illustration of how macro scale synteny varies markedly between the B. oleracea and A. thaliana genomes; unambiguous integration of the B. oleracea cytogenetic and genetic linkage maps; a cross species characterisation of a large collinear inverted segmental duplication on a single B. oleracea chromosome establishing that the relative physical distances have stayed approximately the same; retrotransposon copy number estimations and characterisation of their genomic organisation and isolation, characterisation and cross species analysis of a C genome specific repeat. For each paper the AUTHOR’S individual scientific contribution to each aspect of the work is described in detail. Both individually and as a body of work these publications substantially advance the fields of comparative, Brassica and genomic research.
Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:560430 |
Date | January 2012 |
Creators | Ryder, Carol D. |
Publisher | University of Warwick |
Source Sets | Ethos UK |
Detected Language | English |
Type | Electronic Thesis or Dissertation |
Source | http://wrap.warwick.ac.uk/51651/ |
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