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A cephalometric comparison of children with Down's Syndrome and their normal siblings

Indiana University-Purdue University Indianapolis (IUPUI) / The mongoloid face and craniofacial skeleton
has been characterized by many investigators using
clinical impressions and soft tissue measurements
on living and autopsy material. Few studies have
included data derived from cephalometric radiographs.
The present study was designed to describe the mongoloid
face and cranial base and to analyze the
data.
Twenty mongoloid children ranging in age
from three years to 12 years, and their siblings
were selected for study. A control group of
children were selected on the basis of their essentially
normal occlusion and facial skeleton.
The data obtained from the cephalometric radiographs
were analyzed in three ways. Each of the three groups
of children, normal, mongoloid and their
siblings were divided into four age groups, approximately
three, five, seven and 11 years of age and
means for the individual measurements were calculated.
The sibling measurements were "corrected” to the
age of the mongoloid child using the growth progression
data from the normal children. The mean measurements of the
“corrected” siblings and mongoloids were
then compared using “t” tests for statistical significance. All children
were then divided into three comparison pairs, normal-sibling, normal-mongoloid, and mongoloid-sibling, and the cephalometric measurements
subjected to a multivariate, step-wise regression analysis.
The growth of the maxillae and mandible were retarded in the
Mongoloid children. The maxilla and mandible were positioned
anteriorly under the cranial base.

Identiferoai:union.ndltd.org:IUPUI/oai:scholarworks.iupui.edu:1805/3708
Date January 1966
CreatorsLandau, Macy J. (Macy Jack), 1937-
Source SetsIndiana University-Purdue University Indianapolis
Languageen_US
Detected LanguageEnglish
TypeThesis

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