Efficacy of a sustained-release formulation of bST was evaluated for two consecutive lactations. Response in milk and milk component yield was positive and very consistent for multiparous cows between lactations. Average responses in milk production for the first lactation and for the 320-, 640-, and 960-mg$ cdot$28d$ sp{-1}$ doses of bST were 4.3, 5.2 and 5.9 kg$ cdot$d$ sp{-1}$, respectively. Response was 4.9 kg$ cdot$d$ sp{-1}$ for the average of the second lactation with 640 mg bST$ cdot$28d$ sp{-1}$. Primiparous cows responded with the same numerical magnitude as multiparous cows but with higher variability. BST caused a response in milk yield irrespective of the stage of lactation when injections commenced, but the magnitude of response was greater at latter stages of lactation. No adverse effect of treatment on final body condition score and achievement of proper condition for a subsequent lactation was found. No effect of treatment was observed on health parameters in either lactation. Trends towards longer days open and more breedings per conception were apparent for both lactations. Total milk protein, caseins and whey proteins were not changed at any stage of lactation and for the average of the full lactation. BST did not significantly change proportions of $ alpha sb{s}$-, $ beta$- and K-caseins. Milk fat percentage and milk fatty acid profiles were not different between control and any dose level of bST for a complete lactation. Maximum response in milk yield for the different doses of bST was from d8 to 12 of the 28d cycle and was almost eliminated by d22 to 24. A 3.1 and 3.6 kg$ cdot$d$ sp{-1}$ milk augmentation with bST was estimated in cows infused for 6d with glucose and saline, respectively during peak lactation. There was no apparent milk yield response when cows were infused with insulin + glucose but cows exhibited positive energy balance, weight gain and only 5% less milk. Insulin + glucose infusion increased milk protein 11% and 14% compa
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.41664 |
| Date | January 1993 |
| Creators | Leonard, Martin |
| Contributors | Block, Elliot (advisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Doctor of Philosophy (Department of Animal Science.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 001385067, proquestno: NN94659, Theses scanned by UMI/ProQuest. |
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