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Oncologists' perceptions of the ethical, legal and social implications of genetic testing and microfluidic lab-on-chip technology

The objectives of this study are twofold: firstly, to give an account of the current methods of knowledge production, and secondly to contribute a consultation piece on oncologists perceptions of non-technical issues regarding the ethical, legal and social implications of microfluidic lab-on-chip technology (MF LOC). Two connected theses statements are put forth. First, understanding the transformations of knowledge production will allow for a more socially and ethically informed mode of governance to emerge. Second, it is important to consider who might use the technology and how it might impact institutions and individuals. <p>Interviews were conducted with 31 Canadian oncologists during August 2004 to February 2005. Qualitative analysis was used to examine the oncologists responses. It was found that of the different types of knowledge production that were reviewed (Mode-1, Mode-2, Triple Helix, and Post-normal science) the Triple Helix thesis was most supported. However, an integration of characteristics of Mode-2 with the Triple Helix thesis best accounts for the current description of knowledge production. The principles inherent in Post-Normal Science provide a starting point for developing an approach for building capacity for an independent institution that examines the ethical, legal and social concerns regarding transformative technologies. In relation to the second thesis, the results indicate that MF LOC devices have great potential to transform institutional practices and affect individual lives. And it is important to understand that the oncologists studied constructed their understanding of MF LOC technology within a scientific and biomedical repertoire consequently, future research should assess the perceptions and concerns of other groups of people that are different from the scientific and biomedical repertoire.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:SSU.etd-06132006-183655
Date14 June 2006
CreatorsWallin, Crystal
ContributorsMehta, Michael D.
PublisherUniversity of Saskatchewan
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
Typetext
Formatapplication/pdf
Sourcehttp://library.usask.ca/theses/available/etd-06132006-183655/
Rightsunrestricted, I hereby certify that, if appropriate, I have obtained and attached hereto a written permission statement from the owner(s) of each third party copyrighted matter to be included in my thesis, dissertation, or project report, allowing distribution as specified below. I certify that the version I submitted is the same as that approved by my advisory committee. I hereby grant to University of Saskatchewan or its agents the non-exclusive license to archive and make accessible, under the conditions specified below, my thesis, dissertation, or project report in whole or in part in all forms of media, now or hereafter known. I retain all other ownership rights to the copyright of the thesis, dissertation or project report. I also retain the right to use in future works (such as articles or books) all or part of this thesis, dissertation, or project report.

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