Yes / Pain and delirium are common in people with dementia admitted to hospitals. These are often under-diagnosed
and under-treated. Pain is implicated as a cause of delirium but this association has not been investigated in this setting.
To investigate the relationship between pain and delirium in people with dementia, on admission and throughout
a hospital admission.
Design: Exploratory secondary analysis of observational prospective longitudinal cohort data.
Setting: Two acute hospitals in the UK.
Methodology: Two-hundred and thirty participants aged ≥70 years were assessed for dementia severity, delirium
((Confusion Assessment Method (CAM), pain (Pain Assessment in Advanced Dementia (PAINAD)) scale and prescription
of analgesics. Logistic and linear regressions explored the relationship between pain and delirium using cross-sectional data.
Results: Pain at rest developed in 49%, and pain during activity for 26% of participants during their inpatient stay. Incident
delirium developed in 15%, of participants, and 42% remained delirious for at least two assessments. Of the 35% of participants
who were delirious and unable to self-report pain, 33% of these participants experienced pain at rest, and 56 experienced
pain during activity. The odds of being delirious were 3.26 times higher in participants experiencing pain at rest (95%
Confidence Interval 1.03–10.25, P = 0.044).
Conclusion: An association between pain at rest and delirium was found, suggesting pain may be a risk factor for delirium.
Since pain and delirium were found to persist and develop during an inpatient stay, regular pain and delirium assessments
are required to manage pain and delirium effectively. / The Impact of Acute Hospitalisation on People with Dementia: The Behaviour and Pain (BepAID Study (jointly funded by the Alzheimer’s Society and BUPA foundation (Grant reference number: 131). Dr Sampson’s, Dr White’s, Dr Kupeli’s and Miss Vickerstaff ’s posts are supported by Marie Curie core funding, grant (MCCC-FCO-16-U).
| Identifer | oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/16602 |
| Date | 25 August 2018 |
| Creators | Feast, A.R., White, N., Lord, Kathryn, Kupeli, N., Vickerstaff, V., Sampson, E.L. |
| Source Sets | Bradford Scholars |
| Language | English |
| Detected Language | English |
| Type | Article, Published version |
| Rights | © 2018 The Author(s). Published by Oxford University Press on behalf of the British Geriatrics Society. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
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