Indiana University-Purdue University Indianapolis (IUPUI) / This study was designed to determine if additional fluoride, ingested
as a sodium fluoride - vitamin supplement would provide added protection
against dental caries without causing any significant fluorosis.
A total of 456 children, one to 14 months of age, residing in cities
having 0.6 - 0. 8 ppm F in the water supply were randomly assigned according
to age, sex and community to the following groups : Group A, 0. 5 mg F
to age 3 then 1. 0 mg thereafter; Group B (control), vitamins throughout
the study; and Group C, 0.5 mg F throughout the study.
Dental examinations were started at approximately 2 1/2 to 3 years
of age and were repeated every six months. A fluorosis examination
ended the study after about seven years.
When compared according to length of time on product, Group A had
a significant reduction in deft and defs of 42.2 and 47.1 percent at
60 months. Group C had a 32.1 and 37.4 percent reduction. When compared
by age, Group A had a 37.5 and 44.8 percent reduction in deft and defs
at 66 months. Group C had a 34.3 and 40.1 percent reduction for the
same period. No significant reductions were observed in permanent teeth.
Based on the fluorosis index (Group A - 0.250; Group B - 0.033; and
Group C - 0.188) none of the groups had any unacceptable amounts of
fluorosis.
The results indicate that up to 1.0 mg per day of additional fluoride
does not cause objectionable fluorosis and may be ingested safely by
children residing in areas containing 0. 6 - 0. 8 ppm F in the water
supply. A 0.5 mg F supplement was almost as effective as a 1.0 mg level in providing added protection against dental caries in primary teeth.
| Identifer | oai:union.ndltd.org:IUPUI/oai:scholarworks.iupui.edu:1805/4140 |
| Date | January 1975 |
| Creators | Hennon, David Kent, 1933- |
| Contributors | Roche, James R., 1924-, El-Kafrawy, Abdel Hady, 1935-, Bixler, David, Katz, Simon, 1920-1987, Standish, S. Miles, 1923-2003, Mitchell, David F. |
| Source Sets | Indiana University-Purdue University Indianapolis |
| Language | en_US |
| Detected Language | English |
| Type | Thesis |
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