The following study investigates the intramolecular and intermolecular interactions responsible
for invoking stereoselectivity and stereospecificity in the synthesis of a chiral original species and amino
acid receptor. The former commences with a brief overview of the nature, scope and applications of
helical chirality, and culminates in the formation of a permanent helix via the synthesis of a novel chiral
lactone. The latter is discussed as an extension of a naturally occurring cofactor whose identity is
modulated to furnish a tailored receptor selective to the binding of amino-acid enantiomers. The study
and analysis is executed via both synthetic and computational methods.
Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:OTU.1807/25598 |
Date | 31 December 2010 |
Creators | Golas, Ewa |
Contributors | Chin, Jik |
Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
Language | en_ca |
Detected Language | English |
Type | Thesis |
Page generated in 0.002 seconds