Current study demonstrated the impact of heat therapy on skeletal muscle function in a model of Duchenne muscular dystrophy (DMD). The aim of this study was to: (1) examine the impact of treatment temperature on the skeletal muscle adaptation in DBA/2J mice; and (2) determine the impact of repeated HT for 3 consecutive weeks on body composition and skeletal muscle function in D2.mdx, a model of DMD. From study 1, we revealed that HT at 39℃ for 3 weeks significantly promoted relative muscle mass of both EDL and soleus muscle in DBA/2J mice. However, from study 2, HT at 39℃ for 3 weeks does not improve muscle function or increase muscle mass in a mouse model of DMD.
| Identifer | oai:union.ndltd.org:purdue.edu/oai:figshare.com:article/15062319 |
| Date | 28 July 2021 |
| Creators | Bohyun Ro (11191884) |
| Source Sets | Purdue University |
| Detected Language | English |
| Type | Text, Thesis |
| Rights | CC BY 4.0 |
| Relation | https://figshare.com/articles/thesis/IMPACT_OF_HEAT_THERAPY_ON_SKELETAL_MUSCLE_FUNCTION_IN_A_MODEL_OF_DUCHENNE_MUSCULAR_DYSTROPHY/15062319 |
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