Characterization of unique subregions of the caudal lateral striatum : in their conserved expression patterns of dopamine receptors D1 and D2 in rodents and primates / げっ歯類および霊長類の尾側線条体におけるドーパミン受容体D1およびD2の特殊な発現領域の解明 / ゲッシルイ オヨビ レイチョウルイ ノ ビソク センジョウタイ ニオケル ドーパミン ジュヨウタイ D1 オヨビ D2 ノ トクシュナ ハツゲン リョウイキ ノ カイメイ

Description

It was generally accepted that dopamine receptors D1 (D1R)- and D2 (D2R)-expressing neurons are homogeneously and randomly distributed throughout the striatum. However, in reporter transgenic mice, the specific subregions of the caudal lateral striatum have been reported: the D1R-poor zone, in which D2R-expressing neurons are predominant, and the D2R-poor zone, in which D1R-expressing neurons are predominant. The present study demonstrated the presence of these distinct subregions not only in rodents but also in marmosets using endogenous dopamine receptors. We also showed that direct pathway medium spiny neurons in these distinct subregions preferentially project to parvalbumin-positive GABAergic neurons in the dorsal part of the substantia nigra pars lateralis. / 博士(理学) / Doctor of Philosophy in Science / 同志社大学 / Doshisha University

Links & Downloads

1. https://doshisha.repo.nii.ac.jp/?action=repository_uri&item_id=28197
2. http://id.nii.ac.jp/1707/00028189/
3. 脳科学研究科
4. Graduate School of Brain Science
5. BC08627855
6. https://doshisha.repo.nii.ac.jp/?action=repository_action_common_download&item_id=28197&item_no=1&attribute_id=21&file_no=1
7. https://doshisha.repo.nii.ac.jp/?action=repository_action_common_download&item_id=28197&item_no=1&attribute_id=21&file_no=2
8. 34310甲第1172号

Tags

尾側線条体

ドーパミン受容体

黒質外側部

caudal lateral striatum

dopamine receptors

substantia nigra pars lateralis

Additional Fields

Identifer	oai:union.ndltd.org:doshisha.ac.jp/oai:doshisha.repo.nii.ac.jp:00028197
Date	22 March 2021
Creators	緒方 久実子, Kumiko Ogata
Publisher	櫻井 芳雄
Source Sets	Doshisha University
Language	English
Detected Language	English
Type	Thesis or Dissertation
Format	application/pdf
Source	https://doors.doshisha.ac.jp/opac/opac_link/bibid/BB13158511/?lang=0