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Gas chromatographic studies of drugs of abuse

1. The sensitivity obtained even with the free compounds (except morphine) make gas chromatography a good technique for trace analysis of drugs in biological samples.

2. For many of the drugs studied the detector response curves are not linear with sample concentration but the calibration curves are reproducible if care is exercised. This makes quantitative analysis feasible down to 50-100 nanogram levels with proper technique.

3. Long column life is needed for routine analyses. Those columns employed in this work were used continuously for over seven months with no appreciable deterioration. / Master of Science

Identiferoai:union.ndltd.org:VTETD/oai:vtechworks.lib.vt.edu:10919/42851
Date03 June 2010
CreatorsHernández, J. Benjamin Esquivel
ContributorsChemistry, McNair, Harold M., Mason, John G., Wolfe, James F.
PublisherVirginia Tech
Source SetsVirginia Tech Theses and Dissertation
Detected LanguageEnglish
TypeThesis, Text
Formatvi, 92 pages, 1 unnumbered leaves, BTD, application/pdf, application/pdf
RightsIn Copyright, http://rightsstatements.org/vocab/InC/1.0/
RelationOCLC# 08739283, LD5655.V855_1973.E86.pdf

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