M2-like tumor-associated macrophages promote epithelial-mesenchymal transition through the transforming growth factor β/Smad/zinc finger e-box binding homeobox pathway with increased metastatic potential and tumor cell proliferation in lung squamous cell carcinoma / M2様腫瘍関連マクロファージはTGF-β/Smad/ZEB経路を介して肺扁平上皮癌の上皮間葉転換を促進し転移能を高めるとともに腫瘍細胞の増殖を促進する

Description

京都大学 / 新制・課程博士 / 博士(医学) / 甲第25180号 / 医博第5066号 / 京都大学大学院医学研究科医学専攻 / (主査)教授 平井 豊博, 教授 上野 英樹, 教授 金子 新 / 学位規則第4条第1項該当 / Doctor of Medical Science / Kyoto University / DFAM

Links & Downloads

1. http://hdl.handle.net/2433/288614
2. 10.14989/doctor.k25180
3. 14301

Tags

E-cadherin

epithelial-mesenchymal transition

lung squamous cell carcinoma

tumor-associated macrophage

vimentin

490

Additional Fields

Identifer	oai:union.ndltd.org:kyoto-u.ac.jp/oai:repository.kulib.kyoto-u.ac.jp:2433/288614
Date	25 March 2024
Creators	Sumitomo, Ryota
Contributors	スミトモ, リョウタ
Publisher	Kyoto University, 京都大学
Source Sets	Kyoto University
Language	English
Detected Language	English
Type	doctoral thesis, Thesis or Dissertation
Rights	This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. DOI: 10.1111/cas.15987
Relation	https://doi.org/10.1111/cas.15987