The primary purpose of this study was the identification of patients with JME, in order to identify suitable families for studying the nature of the linkage of the syndrome of JME to the HLA (Human Leukocyte Antigen) locus. This search for suitable candidate families necessitated examination of a large number of individuals with a range of IGE syndromes, and patients were classified into these various syndromes. Patients with JME were thereafter investigated further. The study could thus be broken up into three sections: i) Determination of the various syndromes of IGE. ii) Characterisation of JME. iii) Linkage Studies on JME patients.
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uct/oai:localhost:11427/31753 |
| Date | 30 April 2020 |
| Creators | Carr, Jonathan Ambrose |
| Contributors | Eastman, Roland |
| Publisher | Faculty of Health Sciences, Department of Medicine |
| Source Sets | South African National ETD Portal |
| Language | English |
| Detected Language | English |
| Type | Master Thesis, Masters |
| Format | application/pdf |
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