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Incremental and decremental L- and M-cone driven ERG responses: I. Square-wave pulse stimulation.

No / Electroretinograms (ERGs) elicited by transient, square-wave L- and M-cone isolating stimuli were recorded from human trichromatic (n=19) and dichromatic (n=4) observers. The stimuli were generated on a 4 primary LED stimulator and were equated in terms of cone modulation (cone contrast = 0.11) and retinal illuminance (12,000 trolands). L- and M-cone isolated ERGs had waveforms similar to those observed for luminance responses. However, M-cone ERGs exhibited a phase reversal in their responses to onset and offset stimuli relative to the L-cone responses. This on-off response reversal was observed in trichromats but not dichromats. Simultaneous counter-phase and in-phase combinations of L- and M-cone isolating stimuli generated responses that reflected chromatic and luminance processing, respectively. We conclude that L- and M-cone specific ERGs provide a measure of how photoreceptors contribute to post-receptoral mechanisms.

Identiferoai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/10243
Date04 1900
CreatorsMcKeefry, Declan J., Kremers, Jan, Kommanapalli, Deepika, Challa, Naveen K., Murray, I.J., Maguire, John, Parry, Neil R.A.
Source SetsBradford Scholars
LanguageEnglish
Detected LanguageEnglish
TypeArticle, No full-text in the repository

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