Lower educational attainment has been linked to worse chronic pain outcomes, but the reasons for this relationship are unclear. This study analyzed the relationship between level of education and pain outcomes in patients with musculoskeletal pain, and potential psychosocial mechanisms to explain this relationship. We hypothesized that patients with lower educational attainment would report greater pain intensity and interference, and that pain catastrophizing, anxiety, and depression would mediate the relationship between educational attainment and pain. A total of 843 participants (63% female, 78% White, Mage=55.13), diagnosed with a musculoskeletal pain condition [knee osteoarthritis (29%), back pain (57%), and fibromyalgia (14%)], completed questionnaires including demographics, Brief Pain Inventory (BPI), Pain Catastrophizing Scale (PCS), and Hospital Anxiety and Depression Scales (HADS). Pearson correlations and bootstrapped mediation analyses were conducted to examine the relationships among education, psychosocial, and pain variables. Education was inversely correlated with pain intensity and interference, pain catastrophizing, anxiety, and depression (p < .05). Pain catastrophizing significantly mediated the relationship between education and pain intensity (95%CI [-.05, -.01]), and catastrophizing and depression mediated the effects of education on pain interference (95% CI [-.08, -.01]; 95%CI [-.06, -.01]). Anxiety did not mediate either relationship. These findings indicate that greater pain catastrophizing, and in part depression, partly drive the relationship between lower educational attainment and worse pain outcomes. This work importantly aims to reduce pain disparities and provides direction for psychosocial treatment, suggesting that pain catastrophizing may be a particularly critical target in patients with lower education level. / 2026-02-23T00:00:00Z
| Identifer | oai:union.ndltd.org:bu.edu/oai:open.bu.edu:2144/48195 |
| Date | 24 February 2024 |
| Creators | Fentazi, Delia |
| Contributors | Gerstenfeld, Louis C., Meints, Samantha M. |
| Source Sets | Boston University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis/Dissertation |
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