The aims of this study were to evaluate the influence of an extremely low-frequency electromagnetic field (ELF-EMF) on [3H]glucose uptake in the peripheral tissues and organs of rats. Rats were exposed to ELF-EMF (frequency-10 Hz, induction -1.8-3.8 mT) one hour daily for 14 consecutive days. Control animals were sham exposed. On the 15th day (24 hours after last exposure) rats were injected with D-[3H]-6-glucose 500μCi/kg IP. Fifteen minutes later animals were sacrificed by decapitation and peripheral tissues were excised and examined for radioactivity (desintegrations per minute, DPM/ 100 mg wet tissue weight), which expressed [3H]glucose uptake. In most of the examined tissues and organs, such as liver, kidney, heart muscle, cartilage, connective tissue, tendon and skin, [3H]glucose uptake in ELF-EMF-exposed animals was significantly higher as compared to that in the sham control. Exposure to ELF-EMF did not influence [3H]glucose uptake in the thoracic aorta and the skeletal muscle. It is concluded that ELF-EMF impacts tissue glucose uptake by facilitating glucose transport via cell membranes, dependent and probably also independent of its role in increasing insulin action in insulin-dependent tissues.
| Identifer | oai:union.ndltd.org:ETSU/oai:dc.etsu.edu:etsu-works-19100 |
| Date | 23 April 2007 |
| Creators | Sierón, A., Brus, H., Konecki, J., Cieślar, G., Szkilnik, R., Nowak, P., Noras,, Kwieciński, A., Kostrzewa, R. M., Brus, R. |
| Publisher | Digital Commons @ East Tennessee State University |
| Source Sets | East Tennessee State University |
| Detected Language | English |
| Type | text |
| Source | ETSU Faculty Works |
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