Return to search

The role of synaptic noise in cortical excitability

The entorhinal cortex (EC) is a vital structure in the mammalian brain, implicated in the processes of learning and memory, and a possible site for the generation of seizures in temporal lobe epilepsy. Neurones in the EC are constantly bombarded with inhibitory and excitatory neurotransmitter. This background activity is thought to exert significant control on the excitability and function of neurones in cortical networks, with changes in the levels and proportion of background inhibition (IBg) and excitation (EBg) driving rhythmic oscillations in membrane potential, and even underlying the generation of epileptic seizures.

Identiferoai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:486807
Date January 2008
CreatorsGreenhill, Stuart David
ContributorsJones, Roland
PublisherUniversity of Bath
Source SetsEthos UK
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation

Page generated in 0.0016 seconds