The goal of Synthetic Biology is to engineer systems from biological parts. One class of systems are those whose purpose is to process information. My work seeks to build transcription-based devices for use in combinational digital logic. Preliminary characterization experiments show that existing devices fall short of desired device behavior. I propose to develop a novel implementation of transcription-based logic by designing synthetic transcription factors from well-characterized DNA binding and dimerization domains. Initial modeling work serves to inform design of these devices. / Poster presented at the 2005 ICSB meeting, held at Harvard Medical School in Boston, MA.
| Identifer | oai:union.ndltd.org:MIT/oai:dspace.mit.edu:1721.1/29801 |
| Date | 20 October 2005 |
| Creators | Shetty, Reshma P., Knight, Thomas F. Jr |
| Publisher | Sixth International Conference on Systems Biology |
| Source Sets | M.I.T. Theses and Dissertation |
| Language | en_US |
| Detected Language | English |
| Type | Other |
| Format | 186621 bytes, application/pdf |
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