There are various kinds of noise that affects DNA array data and it is a challenge to obtain high quality data from an experiment. Background correction is a first step for DNA array data processing; however, current methods for background correction have disadvantages. In this thesis, I propose a mixture model to facilitate the background correction for DNA array data generated by ImaGene. The corresponding software is also provided.
| Identifer | oai:union.ndltd.org:uvic.ca/oai:dspace.library.uvic.ca:1828/2550 |
| Date | 12 April 2010 |
| Creators | Chang, Shan |
| Contributors | Lesperance, M. L. |
| Source Sets | University of Victoria |
| Language | English, English |
| Detected Language | English |
| Type | Thesis |
| Rights | Available to the World Wide Web |
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