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Immune responses to Nippostrongylus brasiliensis in Interleukin-5 transgenic mice / Christine M. Daly.

Copies of author's previously published articles in plastic pocket inside back end-paper. / Errata is pasted onto front end-papers. / Bibliography: leaves 181-208. / xi, 208, [161] leaves, [28] leaves of plates : ill. (chiefly col.) ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Demonstrates that resistance to primary N. brasiliensis occurs within the first twenty-four hours of a primary infection in Interleukin-5 (IL-5) transgenic mice. Reduced parasite fecundity within the small intestines of this host appears to result from a culmination of early attrition at the inoculation site and lungs, in addition to adverse events in the local intestinal environment. Implies that eosinophils and not some other indirect consequence of over-expression of IL-5 are responsible for this resistance. / Thesis (Ph.D.)--University of Adelaide, Dept. of Microbiology and Immunology, 1999

Identiferoai:union.ndltd.org:ADTP/260746
Date January 1999
CreatorsDaly, Christine M. (Christine Marie)
Source SetsAustraliasian Digital Theses Program
Languageen_US
Detected LanguageEnglish

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