Navigation and episodic memory are both fundamental cognitive processes that rely on the hippocampus and its connections to other cortical areas. However, the extent and nature of their interdependence is unclear. We investigated how they relate by testing children (8-13 years, i.e., over the age at which skills are refined towards adult levels) and young adults using a real-world encoding experience, and multiple tests of spatial and episodic memory. We found that the measures formed two latent factors. The memory structure factor included measures that require simultaneously representing all or part of the environment (finding routes, mapping the space, free recall of the experience, and spatial-temporal recognition). The perceptual/factual/locale factor included perceptual and semantic recognition along with JRD (which taxes egocentric and allocentric navigation). Univariate BOLD analysis identified a neural architecture that supports representations across both factors: right hippocampus (HC), lateral occipital area (LO), and entorhinal (ERC), perirhinal (PRC), and parahippocampal (PHC) cortices. Pattern analysis revealed that stable similarity of encoded representations in the anterior right HC related to better performance on the memory structure factor. Stable differentiation of encoded representations in the ERC related to better performance for both factors. Additionally, we found a developmental timeline that extends into early adolescence for spatial representations in the ERC and PRC and for stability of encoded information in the LO. In sum, we found that episodic memory and spatial representations are intertwined in the real world, in which humans seldom operate only spatially or only episodically. / Psychology
| Identifer | oai:union.ndltd.org:TEMPLE/oai:scholarshare.temple.edu:20.500.12613/10319 |
| Date | 05 1900 |
| Creators | Nguyen, Kim, 0000-0002-5771-1327 |
| Contributors | Newcombe, Nora, Olson, Ingrid R., Murty, Vishnu P., Chein, Jason M., Olino, Thomas, Epstein, Russell A. |
| Publisher | Temple University. Libraries |
| Source Sets | Temple University |
| Language | English |
| Detected Language | English |
| Type | Thesis/Dissertation, Text |
| Format | 76 pages |
| Rights | IN COPYRIGHT- This Rights Statement can be used for an Item that is in copyright. Using this statement implies that the organization making this Item available has determined that the Item is in copyright and either is the rights-holder, has obtained permission from the rights-holder(s) to make their Work(s) available, or makes the Item available under an exception or limitation to copyright (including Fair Use) that entitles it to make the Item available., http://rightsstatements.org/vocab/InC/1.0/ |
| Relation | http://dx.doi.org/10.34944/dspace/10281, Theses and Dissertations |
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