The tolyporphin A structure contains a tetrapyrrolic bacteriochlorin macrocycle and also consists of two glycosyl groups directly connected to the pyrroles. In this thesis, 3-glycosylated pyrrole was reacted with Eschenmoser's salt to produce N,N-dimethylamino methylated derivative in 95 % yield. Then, the product was reacted with pyrrole under microwave irradiation to produce glycosylated dipyrromethane in 44 % yield. Mono-glycosylated porphyrin was formed by reacting glycosylated dipyrromethane with 1,9-bis (imino)-5-phenyl dipyrromethane under the standard procedure, 1H NMR was used to confirm the new products.
Identifer | oai:union.ndltd.org:UPSALLA1/oai:DiVA.org:uu-307951 |
Date | January 2016 |
Creators | Al-Smadi, Derar |
Publisher | Uppsala universitet, Organisk kemi |
Source Sets | DiVA Archive at Upsalla University |
Language | English |
Detected Language | English |
Type | Licentiate thesis, monograph, info:eu-repo/semantics/masterThesis, text |
Format | application/pdf |
Rights | info:eu-repo/semantics/openAccess |
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