The purpose of this study was to optimize and investigate crown ether analysis by using a mass spectrometer equipped with a direct insertion solids probe. The typical aliphatic and aromatic crowm ethers, 18-crown-6 and dibenzo-18-crown-6 were chosen for the study. The crown ether samples were prepared by miximg with the reagents (some inorganic and organic salts and glycine) or being supported on the support materials (diatomite and glass supports) in a 1:10 ratio by weight as the samples for testing. The pure crown ethers and their mixtures were tested by the programmed temperature direct insertion probe mass spectrometer. The effects of the reagents and support materials on the peak maximum temperature (Tm) and the spectra of the crown ethers were studied. The results Tm of the crown ethers to increase significantly, and glycine and ammonium salts interfered the spectra of the crown ethers. The effect of sample size and "concentration" on Tm of the crowns also was investigated. The bigger sample size caused the Tm to be higher. No significant effect of the "concentration" on Tm was observed. It was concluded that tha smaller sample size provided better spectra with less interfererences and that some thermally stable reagents or support materials could be used to facilitate the sampling of crown ethers. More detailed study of the effects of iodides on Tm was recommended. In addition, more detailed investigation of the approach of using a CI source without reagent gases is needed. Switching to the CI configuration appears to be a simple and effective method for providing complementary information about the molecules.Ball State UniversityMuncie, IN 47306
| Identifer | oai:union.ndltd.org:BSU/oai:cardinalscholar.bsu.edu:handle/183467 |
| Date | 03 June 2011 |
| Creators | Qian, Weiguang |
| Contributors | Kruger, Terry L. |
| Source Sets | Ball State University |
| Detected Language | English |
| Format | vi, 53 leaves : ill. ; 28 cm. |
| Source | Virtual Press |
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