With Hench's (1) announcement of the dramatic effect of cortisone on rheumatoid arthritis - attention was suddenly focused on this hormone and on ACTH, the pituitary corticotropic hormone. These substances are by no means newly discovered. In 1935 - Kendall (2) isolated Compound E from the cortex of the adrenal, and in 1938, established its formula as 17 hydroxy - 11 dehydro cortico sterone. In 1946 Sarett (3) established a partial synthesis of this substance as a 24 hour procedure starting with a bile acid - desoxycholic acid.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.108632 |
| Date | January 1952 |
| Creators | Schiller, Carl. |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science. (Department of Experimental Surgery.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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