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Blood damage in prolonged extra-corporeal circulation.

The first open-heart operation involving the use of an artificial heart-lung machine was performed by Gibbon (1954). However, this concept of artificial maintenance of the cardio-respiratory function had been considered over a century before. In 1812 Legallois stated "If one could substitute for the heart a kind of injection of arterial blood either natural or artificially made, one would succeed easily in maintaining alive indefinitely any part of the body whatsoever." Commencing with the development of in vitro perfusion of isolated organs by physiologists such as Starling (1925), work in this field led gradually to the design of blood pumps and artificial oxygenators capable of supporting the entire circulation.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.113579
Date January 1961
CreatorsWright, Earle. S.
ContributorsMurphy, D. (Supervisor)
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageMaster of Science. (Department of Health Sciences.)
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relationalephsysno: NNNNNNNNN, Theses scanned by McGill Library.

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