Recent experimental studies have thrown considerable light on some of the mechanisms acting to produce the picture of irreversible shock. These have emphasized the importance of the liver (104), the capillary “pool” (12,105), and bacterial toxins probably originating from bacteria in the portal system, and prior to this the bacterial flora of the intestines (33,37). There are, however, very few studies on the possible role or roles played by the lungs during the shock process to be found in the literature. A few authors have written on the pathological picture (69,77) which may or may not be present; others have studied the circulation of the blood (27,60) and lymph following hemormage and tourniquet shock; and still others have studied the oxygen content of the mixed venous and the arterial blood during various forms of shock (94). Careful study of these and other articles, however, does not leave the reader completely satisfied as to the actual role of the lungs. Do they have a primary function in the response of the body to the decreased circulating blood volume that may eventuate in irreversible shock? Or are they merely passive reactors in the chain of events? Undpubtedly, in tbose cases where the congestive and other changes have became advanced, the normal respiratory functions must be unfavourably effected; but is there a basic pulmonary effect that is being obscured?[...]
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.123876 |
| Date | January 1952 |
| Creators | Rounthwaite, Harry L. |
| Contributors | Webster, D. (Supervisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science. (Department of Experimental Surgery.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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