Gene expression arrays are used to assess expression of exons and genes of orga- nisms. The design of expression arrays is based on a genome of laboratory strains of model organisms. The most frequent summarization algorithms used to pro- cess data from measurements are gcRMA, PLER and IterPLIER. When using expression arrays to research free living species, the measured values are influen- ced by differences in genomes of free living and model organisms. We propose a method to improve the results by removing parts of genomes influenced by known differences between species from the summarization. Removing influenced parts can improve summarization, especially on exon level. 1
| Identifer | oai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:347555 |
| Date | January 2016 |
| Creators | Tuma, Vojtěch |
| Contributors | Mořkovský, Libor, Vomlelová, Marta |
| Source Sets | Czech ETDs |
| Language | Czech |
| Detected Language | English |
| Type | info:eu-repo/semantics/masterThesis |
| Rights | info:eu-repo/semantics/restrictedAccess |
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