Glucose-6-phosphate dehydrogenase (G6PD) is a cytoplasmic enzyme with an important function in cell oxidative damage prevention. Erythrocytes have a predisposition towards oxidized environments due to their lack of mitochondria, giving G6PD a major role in its stability. G6PD deficiency (G6PDd) is the most common enzyme deficiency in humans; it affects approximately 400 million individuals worldwide. The overall G6PDd allele frequency across malaria endemic countries is estimated to be 8%, corresponding to approximately 220 million males and 133 million females. However, there are no reports on the prevalence of G6PDd in Andean communities where bartonellosis is prevalent.
Identifer | oai:union.ndltd.org:PERUUPC/oai:repositorioacademico.upc.edu.pe:10757/595273 |
Date | 01 1900 |
Creators | Mazulis, Fernando, Weilg, Claudia, Alva Urcia, Carlos Alberto, Pons, Maria J, Del Valle Mendoza, Juana |
Publisher | Elsevier B.V. |
Source Sets | Universidad Peruana de Ciencias Aplicadas (UPC) |
Language | English |
Detected Language | English |
Type | info:eu-repo/semantics/article |
Format | application/pdf |
Source | Universidad Peruana de Ciencias Aplicadas (UPC), Repositorio Académico - UPC |
Rights | info:eu-repo/semantics/openAccess |
Relation | https://www.researchgate.net/publication/284136837_Is_glucose-6-phosphate_dehydrogenase_deficiency_more_prevalent_in_Carrion's_disease_endemic_areas_in_Latin_America |
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