Atrial fibrillation is the most frequent clinically significant arrhythmia. Its occurrence in adult population was previously reported to be 0.4 %, currently it is more or less 0.95 %. In industrial countries the population of patients with ischemic heart disease is increasing; with progress in therapy of such patients the number of individuals with heart disease has increased. Increasing prevalence of atrial fibrillation, which occurs frequently with such diseases, is also expected. Concurrence with atrial flutter, atrial macroreetnry arrhythmia is relatively frequent. Both arrhythmias may alternate in a patent or change from one to another. Efforts with medication therapies were not sufficiently successful in the past. New products have been sought all the time – the products which would have influence on the atrial muscle and have no influence on ventricular myocardium, have no side effects and no proarrhythmogenic potential. Simultaneously, ways of non-pharmacological treatment have been sought. The non-pharmacological methods are prevailing currently since pharmaceutical products fail and have irregular effect. The category of non-pharmacological treatment includes cardio-stimulating methods and ablation techniques. Accordingly, there were no sufficiently sophisticated methods of evaluating of arrhythmia occurrence after ablation procedures. The development of efficient detection, processing and evaluation of heart activity proceeds to long-term monitoring of heart signals using an implantable heart monitor. The latest model of implantable heart monitor has been introduced in clinical practice; it is particularly intended for diagnostics of atrial arrhythmias. The above-mentioned implant bears trade name REVEALŽ XT, produced by the MEDTRONIC Company. This thesis elaborates comprehensively the issue of implantable heart monitors of the latest generation which are specially intent on diagnostics of atrial arrhythmias. It summarizes data that was collected as a part of two world-wide multicentre studies EPECT and VISIT. In this thesis I analyze data obtained at the centre of acute cardiology hospital Na Homolce. The data population offers a comprehensive view of potentials of subcutaneous heart monitors from the pre-implanting phase to one-year follow-up of detection properties and classifications of heart arrhythmias with a strong emphasis on an analysis of atrial tachyarrhythmias. Based on thus analyzed data the following conclusion can be made: The implantable heart monitor REVEALŽ XT is suitable for clinical applications of long-term monitoring of heart rhythm both in the area of ventricular and atrial arrhythmias.
| Identifer | oai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:374850 |
| Date | January 2009 |
| Creators | Vopálka, Roman |
| Contributors | Tyšler,, Milan, Šimurda, Jiří, Jan, Jiří |
| Publisher | Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií |
| Source Sets | Czech ETDs |
| Language | Czech |
| Detected Language | English |
| Type | info:eu-repo/semantics/doctoralThesis |
| Rights | info:eu-repo/semantics/restrictedAccess |
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