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Development of non-invasive procedure for evaluating absolute intracranial pressure based on finite element modeling

Elevated intracranial pressure (ICP) in closed head injury may lead to a vegetative state and even death. Current methods available for measuring ICP may cause infection, haemorrhage or not reliable. A patient-specific correlation between ICP and an external vibration response was used for ICP evaluation, which based on finite element (FE) modeling. In FE modeling, a two dimensional FE model of human head was built in ANSYS. Geometry information was obtained from a magnetic resonance image of the human head, while the material properties were acquired from literatures. Vibration responses, e.g., displacement, velocity, acceleration and equivalent strain, were obtained for applied ICPs in FE analyses. Correlations between ICP and vibration responses were established. Effects of impact magnitude and impact duration were studied. Response sensitivity was defined to find a vibration response that is sensitive to ICP change. A procedure based on response sensitivity was proposed for ICP evaluation.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:MWU.1993/4114
Date09 September 2010
CreatorsLi, Zhaoxia
ContributorsLuo,Yunhua (Mechanical and Manufacturing Engineering) Zhang,Qiang (Biosystems Engineering), Peng,Qingjin (Mechanical and Manufacturing Engineering) Cai,Jun (Electrical and Computer Engineering)
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
Languageen_US
Detected LanguageEnglish

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