Photochromic Molecular Flow Visualization is an in vitro, experimental technique that uses high speed image acquisition combined with an ultraviolet laser to capture instantaneous flow profiles. It is particularly adept at measuring near wall velocities which are necessary for accurate wall shear rate measurements. This thesis describes the implementation and validation of the technique at McGill. The system was used to investigate the wall shear rate patterns in an idealized 50% asymmetric stenosis model under steady flow for Reynolds numbers 206, 99 and 50. A large recirculation zone with flow reattachment was seen downstream of the stenosis with maximum shear values occurring slightly upstream of peak stenosis for Reynolds number 206. This information is vital to ongoing dynamic cell culture experiments aimed at understanding the progression of atherosclerosis.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.111613 |
| Date | January 2008 |
| Creators | Chin, David, 1982- |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Engineering (Department of Chemical Engineering.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 003135105, proquestno: AAIMR66917, Theses scanned by UMI/ProQuest. |
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