Indiana University-Purdue University Indianapolis (IUPUI) / Two of the three fluoride varnishes sold on the American market today are sold in
10-ml tubes of 5.0-percent NaF varnish (Duraphat and Duraflor). Pilot studies have
shown that a separation of contents within these tubes exists. The purpose of the current
study was four-fold: 1) to measure the fluoride concentration gradient in 10-ml tubes of
fluoride varnish, based on the resting position of the tube prior to use; 2 ) to compare a
varnish 's concentration gradient to its ability to inhibit caries in an artificial caries
environment; 3) to compare and contrast fluoride concentration gradients of Duraphat
and Duraflor; and finally, 4) to determine if Quantitative Light Fluorescence(QLF) can
detect differences in lesions developed when exposed to an artificial caries environment
and fluoride varnish. Human teeth specimens were subjected to a caries challenge and
treated with a sample of fluoride varnish from one of five categories: Duraphat stored
horizontally and vertically for one week; Duraflor stored horizontally and vertically for
one week; or a CavityShield 0.4 ml unit-dose. Results show that no significant
fluoride/ppm differences exist between groups (p = 0.29). It was shown that the order in
which Duraflor varnish was dispensed from the tubes significantly affected the fluoride
concentration (p < 0.05). The order effect was not significant for Duraphat (p = 0.99).
QLF data analysis shows there is no significant difference (p > 0.05) in the amount of
remineralization obtained by using any varnish stored in any position. This was
confirmed using confocal microscopy. These results indicate that all three brands of
fluoride varnish are able to remineralize incipient in vitro carious lesions, regardless of
from which part of the 10-ml tube the varnish is taken. However, a fluoride
concentration gradient exists in tubes of Duraflor. Also, QLF is able to detect
denmineralized and remineralized incipient lesions.
| Identifer | oai:union.ndltd.org:IUPUI/oai:scholarworks.iupui.edu:1805/3677 |
| Date | January 2001 |
| Creators | Hazelrigg, Chad Owen |
| Contributors | Dean, Jeffrey A., Stookey, George K., Hazelrigg, Charles O., Zunt, Susan L., 1951-, Fontana, Margherita Ruth, 1966- |
| Source Sets | Indiana University-Purdue University Indianapolis |
| Language | en_US |
| Detected Language | English |
| Type | Thesis |
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