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A study of the teratogenicity of diphenylhydantoin and phenobarbitone in the experimental mouse

The aims of the research were to establish whether diphenylhydantoin and phenobarbitone are teratogenic in mice both in vivo and in an in vitro whole embryo culture system, to investigate possible mechanisms of teratogenicity and to examine whether the methods used in this study, may form a basis for developing systems of more extensive drug teratogenicity screening.

Identiferoai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uct/oai:localhost:11427/26474
Date04 August 2017
CreatorsBeyers, Nulda
ContributorsFolb, Peter I
PublisherUniversity of Cape Town, Faculty of Health Sciences, Division of Clinical Pharmacology
Source SetsSouth African National ETD Portal
LanguageEnglish
Detected LanguageEnglish
TypeMaster Thesis, Masters, MSc
Formatapplication/pdf

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