Recent investigations into the permeability of the kidney capillaries have produced conflicting reports. This study was an attempt to better describe the permeability of the kidney capillaries by using narrow-range macromolecular dextran fractions in four molecular sizes: MW 61,400, MW 77,000, MW 118,000, and MW 147,000. Permeability was measured by dextran concentration differences in plasma and kidney lymph. Permeability decreased as the dextran molecular weight increased. Molecular weights 61,400 and 77,000 penetrated into the kidney lymph. Molecular weight 118,000 exhibited greater difficulty in penetrating to the lymph. The largest fraction penetrated into the kidney lymph with greatest difficulty. Plasma expansion by saline infusion increased the permeability of all dextran fractions.
| Identifer | oai:union.ndltd.org:unt.edu/info:ark/67531/metadc504185 |
| Date | 08 1900 |
| Creators | Wooldridge, Clayton Bradley |
| Contributors | Redden, David R., Lott, James R., Mrotek, James J. |
| Publisher | North Texas State University |
| Source Sets | University of North Texas |
| Language | English |
| Detected Language | English |
| Type | Thesis or Dissertation |
| Format | vi, 97 leaves: ill., Text |
| Rights | Public, Wooldridge, Clayton Bradley, Copyright, Copyright is held by the author, unless otherwise noted. All rights reserved. |
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