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Previous issue date: 2014-12-08 / Introdu??o: Estimula??o transcraniana por corrente continua (ETCC) tem sido
usada em estudos voltados para o tratamento da dor perif?rica cr?nica em pessoas
com les?o medular (LM), mas seus efeitos sobre o sistema nervoso auton?mico
(SNA) nestes indiv?duos s?o inexistentes e, portanto a necessidade de estudos ? de
fundamental import?ncia, pois estes indiv?duos apresentam desbalan?o auton?mico,
e sua intensidade ? dependente do grau e n?vel da les?o. Objetivo: Investigar se a
ETCC sobre o c?rtex motor prim?rio ir? modular o controle do SNA em pessoas com
LM e se estas altera??es s?o dependentes do grau e n?vel de les?o. M?todos:
Estudo randomizado, placebo controlado, aplicou ETCC an?dica ou sham sobre o
c?rtex motor prim?rio (M1), bilateralmente, com o eletrodo de refer?ncia sendo
colocado na protuber?ncia occipital. Dezenove sujeitos (les?o incompleta baixa
(n=7), completa baixa (n=9) e completa alta (n=3)) visitaram o laborat?rio tr?s vezes
e receberam ETCC ativa ou sham por 13min. A variabilidade da frequ?ncia card?aca
(VFC) foi medida antes, durante e p?s-estimula??o. A VFC foi calculada usando a
analise espectral batimento a batimento dos intervalos derivados das ondas r-r.
Resultados: A ETCC modulou o sistema nervoso auton?mico de forma divergente
nos grupos analisados. Nos indiv?duos com LM completa alta a ETCC n?o alterou a
VFC. Para os indiv?duos com LM incompleta baixa a ETCC alterou a VFC no sentido
de aumentar o simp?tico e reduzir o parassimp?tico e para os indiv?duos com LM
completa baixa a ETCC reduziu o simp?tico e aumentou o parassimp?tico.
Conclus?o: O presente estudo observou que a ETCC an?dica aplicada sobre o
c?rtex motor prim?rio de forma bilateral, conseguiu modular o balan?o do SNA em
pessoas com les?o medular e este efeito ? dependente do grau e n?vel de les?o.
Palavras-chave: Estimula??o Transcraniana; Sistema nervoso auton?mico;
Variabilidade da frequ?ncia card?aca; Les?o medular. / Introduction: Transcranial Direct Current Stimulation (tDCS) has been used in
studies for the treatment of chronic pain, but their effects on the autonomic nervous
system (ANS) are non-existent. Therefore, the need for studies is of fundamental
importance, as these individuals have autonomic imbalance and the intensity of this
is dependent on the degree and level of injury. Objective: We investigated the effect
of tDCS on the ANS in people with spinal cord injury (SCI) with different degrees and
levels of injury. Methods: Randomized, placebo-controlled, double-blind, applied
anodal tDCS or sham on the primary motor cortex (M1), bilaterally. The subjects
(lower incomplete injury, n = 7; lower complete injury, n = 9; and high complete
thoracic injury, n = 3) visited the laboratory three times and received active or sham
tDCS for 13min. The heart rate variability (HRV) was measured before, during and
after stimulation and analyzed the variables LF, HF and LF / HF. Results: The tDCS
modulated the ANS in different ways among the groups. In individuals with SCI high
complete thoracic the tDCS did not change the HRV. However, for individuals with
SCI low incomplete, tDCS changed the HRV in order to increase sympathetic (LF, p
= 0.046) and reduced parasympathetic (HF, p = 0.046). For individuals SCI low
complete to tDCS changed the HRV reduction sympathetic (LF, p = 0.017) and
increased parasympathetic (HF, p = 0.017). Conclusions: The present study
suggests that anodal tDCS applied on the motor cortex bilaterally could modulate the
ANS balance in people with spinal cord injury and that this effect is dependent on the
degree and level of injury.
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.ufrn.br:123456789/19877 |
| Date | 08 December 2014 |
| Creators | Silva, Fabiana Ten?rio Gomes da |
| Contributors | 88516857700, http://lattes.cnpq.br/0392766010188739, Silva, Alair Pedro Ribeiro de Souza e, 81374909734, http://lattes.cnpq.br/9651721850436894, Cabral, Breno Guilherme de Ara?jo Tinoco, 00804970475, http://lattes.cnpq.br/8399135324397066, Egito, Eryvaldo S?crates Tabosa do, Dantas, Paulo Moreira Silva |
| Publisher | Universidade Federal do Rio Grande do Norte, PROGRAMA DE P?S-GRADUA??O EM EDUCA??O F?SICA, UFRN, Brasil |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Source | reponame:Repositório Institucional da UFRN, instname:Universidade Federal do Rio Grande do Norte, instacron:UFRN |
| Rights | info:eu-repo/semantics/openAccess |
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