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Mutagenic Potential of Tetramethylthiuram Disulfide (42-S Thiram) on the Germ Cell Stages of Drosophila melanogaster

Tetramethylthiuram disulfide (42-S Thiram), a carbamate fungicide was studied for its mutagenic potential on the germ cell stages of wild-type male Drosophila melanogaster. The mutagenicity was tested using the sex-linked recessive lethal assay (SLRL). Any lethals induced in the F2 generation were evidenced by the absence of wild-type males. Although there was an increase in mutation rates in the 42-S Thiram treated wild-type males over the control wild-type males, it was not significantly higher. According to the laboratory conditions in this preliminary study, tetramethylthiuram disulfide failed to produce mutagenic effect.

Identiferoai:union.ndltd.org:unt.edu/info:ark/67531/metadc500794
Date12 1900
CreatorsLowe-Chatham, Janice E. (Janice Elaine)
ContributorsWhite, Olivia Masih, O'Donovan, Gerard A., Shanley, Mark Stephen
PublisherUniversity of North Texas
Source SetsUniversity of North Texas
LanguageEnglish
Detected LanguageEnglish
TypeThesis or Dissertation
Formatv, 49 leaves : ill., Text
RightsPublic, Lowe-Chatham, Janice E. (Janice Elaine), Copyright, Copyright is held by the author, unless otherwise noted. All rights reserved.

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