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Early Retinal Neuronal Dysfunction in Diabetic Mice: Reduced Light-Evoked Inhibition Increases Rod Pathway Signaling.

Recent studies suggest that the neural retinal response to light is compromised in diabetes. Electroretinogram studies suggest that the dim light retinal rod pathway is especially susceptible to diabetic damage. The purpose of this study was to determine whether diabetes alters rod pathway signaling.

Identiferoai:union.ndltd.org:arizona.edu/oai:arizona.openrepository.com:10150/604678
Date01 March 2016
CreatorsMoore-Dotson, Johnnie M., Beckman, Jamie J., Mazade, Reece E., Hoon, Mrinalini, Bernstein, Adam S., Romero-Aleshire, Melissa J., Brooks, Heddwen L., Eggers, Erika D.
ContributorsDepartment of Physiology, University of Arizona, Graduate Interdisciplinary Program in Physiological Sciences, University of Arizona, Department of Biomedical Engineering, University of Arizona
PublisherAssociation for Research in Vision and Ophthalmology (ARVO)
Source SetsUniversity of Arizona
LanguageEnglish
Detected LanguageEnglish
TypeArticle
RightsArchived with thanks to Investigative ophthalmology & visual science
Relationhttp://iovs.arvojournals.org/article.aspx?articleid=2511068

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