Return to search

The genetics basis of spontaneous cleft lip in the inbred a/jax mouse strain.

Although genetic studies are devoted, for the most part, to characters showing clear cut segregation, a great many genetically determined defects show familial patterns which cannot be explained by a difference at a single genetic locus or even a very few loci. These defects are often biologically important and, in spite of the difficulties involved in their analysis, deserve more intensive study. The studies which have been done, such as those of Wright (1934a, 1934b), Reed (1936), Gruneberg (1952), Lerner (1954), and Landauer (1957), attempt to explain the apparently non-Mendelian behaviour of the trait in question by invoking either reduced penetrance or multigenic inheritance, or both.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.115405
Date January 1964
CreatorsDavidson, Jefferson. G.
ContributorsFraser, F. (Supervisor)
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageDoctor of Philosophy. (Department of Biology.)
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relationalephsysno: NNNNNNNNN, Theses scanned by McGill Library.

Page generated in 0.1302 seconds