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A controlled examination of impulsivity in terms of the inability to inhibit inappropriate reward-seeking in non-treatment-seeking, non-abstinent pathological gamblers /

Despite growing recognition that impulsivity is associated with pathological gambling (PG), three methodological concerns continue to prevent a meaningful examination of how impulsivity is specifically associated with PG. First, the lack of studies specifically comparing PGs to less severe gamblers leaves the question of whether impulsivity was not also associated with less severe gamblers unexamined. Second, the inadequate control of confounding variables in most studies raises concerns about whether findings that impulsivity is associated with PG may be spurious. Third, many findings that impulsivity is associated with PG are based on unrelated definitions of impulsivity, and are therefore relatively uninformative. / The present series of studies is the first attempt to address all of these concerns at the same time. In terms of appropriate comparison groups, study 1 compared PGs to at-risk gamblers and social gamblers, and study 2 compared severe PGs to moderately severe PGs and social gamblers. In terms of adequate controls, both studies examined PGs who were not in treatment and representative in terms of comorbid drug use. In addition, both studies controlled for age, gender, education, socioeconomic status, psychiatric comorbidity, and general cognitive function. Study 2 furthermore controlled for depression, trait anxiety, aggression, and criminality. In terms of improving how impulsivity is examined, study 1 elaborated a neuroanatomically-based definition of impulsivity and examined how three hypothesized neuroanatomical components of impulsivity were associated with PG. In study 2, different operationalizations of impulsivity, based on the same definition of impulsivity, were examined regarding their association with PG. / Every measure that was directly related to the present definition of impulsivity was significantly associated with severe PGs, and only severe PGs, suggesting that severe PGs may comprise a distinct group of gamblers. Measures which were not directly related to this definition of impulsivity were not significantly different between severe PGs (or PGs in study 1) and less severe gamblers. Severe PGs performed as well or better than social gamblers on retention capacity and attention control measures of working memory. / In conclusion, the inability to inhibit inappropriate reward-seeking is argued to be a primary deficit of severe PGs in our sample.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.115707
Date January 2008
CreatorsLeiserson, Victor.
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageDoctor of Philosophy (Department of Psychology.)
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relationalephsysno: 003131266, proquestno: AAINR66576, Theses scanned by UMI/ProQuest.

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