New technologies are making it possible to engineer organisms with fundamentally new and useful properties. In vivo genome engineering technologies capable of manipulating genomes from the nucleotide to the megabase scale were developed and applied to reassign the genetic code of Escherichia coli. Such genomically recoded organisms show promise for thwarting horizontal gene transfer with natural organisms, resisting viral infection, and expanding the chemical properties of proteins.
| Identifer | oai:union.ndltd.org:harvard.edu/oai:dash.harvard.edu:1/11745697 |
| Date | 25 February 2014 |
| Creators | Lajoie, Marc Joseph |
| Contributors | Church, George McDonald |
| Publisher | Harvard University |
| Source Sets | Harvard University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis or Dissertation |
| Rights | open |
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