Since 1983, the WHO has recommended the use of the INR for measuring the level of anticoagulation for patients receiving warfarin therapy. However, no scientifically-derived guidelines, using the INR, for the surgical management of this group of patients exists. In the first part of this study, the protocols followed by oral surgeons, when treating patients receiving warfarin, and who require dental extractions were established by performing a mail survey. The results of the survey illustrated that although the majority of oral surgeons use the INR, most of them use the INR along with the PT and only one fifth of them use this measure alone. In the second part of this study, dental extractions were performed on rabbits which were anticoagulated to various INR levels. The results of this study strongly suggest that dental extractions may be safely performed on subjects receiving oral anticoagulants using routine measures for local hemostasis.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.28036 |
| Date | January 1997 |
| Creators | Troulis, Maria J. |
| Contributors | Head, T. W. (advisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science (Faculty of Dentistry) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 001643451, proquestno: MQ37316, Theses scanned by UMI/ProQuest. |
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