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Improving the spatial resolution of the MicroPET R4 scanner by wobbling the bed

The MicroPET R-4 scanner was designed for imaging small rodents such as mice and rats. In many cases its spatial resolution is not good enough to perform the required task. We have implemented an eccentric motion (commonly referred to as wobbling) which is applied to the bed during scanning. / The program which histograms the list-mode data was rewritten to increase the spatial sampling by incorporating the wobble position in the sinograms. The corrections for the dwell time, apparent crystal location, and crystal-pair efficiency are applied within the program. A series of scans were performed to decide the optimum wobble radius; it was found to be 1.50 mm. Another series of scans was performed during which a Na-22 source was moved 0.25 mm between scans with and without the optimal wobble motion. The peak-to-valley ratio between two Na-22 point sources 4.0 mm apart, improved from 1.75 in the conventional mode to 2.26 during wobbled scans applying a ramp filter. / The bed wobbling mechanism can he added to the microPET R4 or P4 scanners without any major changes to make wobble motion and without compromising any imaging modes. Implementing the wobble mechanism may present a cost-effective upgrade over a trade in or purchase of the higher performance scanner.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.101799
Date January 2006
CreatorsSuk, Joon Young.
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageMaster of Science (Department of Medical Radiation Physics.)
Rights© Joon Young Suk, 2006
Relationalephsysno: 002585643, proquestno: AAIMR32864, Theses scanned by UMI/ProQuest.

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