The effect of a single exposure of He-Ne laser on collagen content was studied in vivo using laboratory animals. A standardized 1.5 cm full thickness skin incision was made on the dorsum of 24 Sprague-Dawley rats. The rats were divided into six equal size groups, three groups functioning as controls and three groups functioning as experimental. The experimental animals were irradiated with He-Ne laser four days post-incision for 16 minutes to deliver a total dose of 5.99 J/cm$ sp2$. On days 6, 10 and 14 post-incision, control and experimental animals had the healing wounds excised for analysis of collagen content by assaying spectrophotometrically the hydroxyproline content within the tissue samples. / The results of the hydroxyproline content were analyzed using independent-groups t-test and analysis of variance. It was demonstrated that even though the mean values of hydroxyproline within the experimental groups were higher than the respective control groups, no statistical significance could be attributed to this observation.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.59641 |
| Date | January 1990 |
| Creators | Ross, Ian William |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science (Faculty of Dentistry.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 001116125, proquestno: AAIMM66381, Theses scanned by UMI/ProQuest. |
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