The purpose of this study was to determine the cumulative doses of x-ray radiation to the thyroid gland and female breast from spinal radiographs for Adolescent idiopathic scoliosis (AIS) and to estimate the number of cancers at these sites attributable to x-rays. / Subjects for this study were patients referred from 1960 to 1979 for AIS to Hopital Ste-Justine, Montreal. / About 85 percent of 2,181 subjects were first referred for scoliosis between the ages of eleven and seventeen and the average time under observation was about three years. The mean number of radiographs was about twelve. The mean cumulative dose to the thyroid gland and to the female breast was about three cGy. Seven excess breast cancer and thyroid cancer cases were projected to occur over the lifetime of the women; among these, two excess deaths from cancers were projected. Approximately one in every 250 women in this cohort would be expected to develop breast or thyroid cancer over their lifetime, and one in every 900 women would be expected to develop a fatal cancer. (Abstract shortened by UMI.)
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.61333 |
| Date | January 1992 |
| Creators | Levy, Adrian R., 1962- |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science (Department of Epidemiology and Biostatistics.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 001307464, proquestno: AAIMM80352, Theses scanned by UMI/ProQuest. |
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